Mechanism of action. Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or Identification - Pharmacology - Interactions - Economics. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral muscarinic subtypes (cardiac and glandular). Trihexyphenidyl partially blocks cholinergic activity in the CNS, which is responsible for the symptoms of Parkinson's disease. Trihexyphenidyl is an oral anticholinergic agent used predominantly in the PubMed Citation (Review of mechanism of action, tolerability and safety of.
Pharmacology. The exact mechanism of action in parkinsonian syndromes is not precisely understood, but it is known that trihexyphenidyl blocks efferent impulses in parasympathetically innervated structures like smooth muscles (spasmolytic activity), salivary glands, and eyes (mydriasis). Adverse effects - Overdose - Interactions - Pharmacology. Prolongation of the gastrointestinal transit time may be the mechanism of the constipating effect. Benzodiazepines: (Moderate) CNS depressants, such as anxiolytics, sedatives, and hypnotics, can increase the sedative effects of trihexyphenidyl. Mechanism of Action. Trihexyphenidyl inhibits the parasympathetic nervous system and has a relaxing effect on smooth muscles.
Trihexyphenidyl (Artane) 1 to mg per day, divided, three to four times a day. Baclofen (Lioresal) 10 to 80 mg . Mechanism of action. The normal inhibition of . Find patient medical information for Trihexyphenidyl Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Mechanism of Action. Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or. Learn about Artane (Trihexyphenidyl) may treat, uses, dosage, side effects, the toxicity may be intensified due to their antimuscarinic action, causing coma.